Between 2009 and 2011, he worked as a Research Assistant at Afyon Kocatepe University. He then served as a Lecturer and Vocational School Vice Director at the same university between 2011 and 2012. From 2012 to 2017, he worked as a Lecturer and Director of a Research Center at Usak University. He was an Assistant Professor at Suleyman Demirel University between 2017 and 2019, and an Associate Professor there from 2019 to 2024. Currently, he is a Full Professor at Suleyman Demirel University, Turkey.

Dr. Kose has also taught at other higher education institutions such as Gazi University and Istanbul Arel University. He served as a Visiting Researcher at the University of North Dakota, USA (2023–2024), and holds the title of Honorary Professor of Artificial Intelligence at ITM (SLS) Baroda University, India.

He has more than 350 publications, including articles, authored and edited books, proceedings, and technical reports. He serves on the editorial boards of many scientific journals and is one of the editors of the Biomedical and Robotics Healthcare (CRC Press) and Computational Modeling Applications for Existential Risks (Elsevier) book series.

His research interests include artificial intelligence, machine ethics, AI safety, biomedical applications, optimization, chaos theory, distance education, e-learning, computer education, and computer science.