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Hematology analyzer is widely used in clinical tests in the hospital. In order to meet the needs of clinical diagnosis, various new detection function has been added to hematology analyzer to achieve joint detection of multiple parameters. Based on rapid software design and extended development methods, the design and implementation of a new intelligent hematology analyzer software are explored in this paper, and the overall design of the control node and management node are introduced, also, the software implementation of the CAN communication module and fault detection mechanism are given. The new intelligent hematology analyzer is based on the functional module of existing three-diff standard hematology analyzer, using a distributed system architecture which adopt CAN bus for communication. The CRP detection is attached to the original routine blood test, extending a new detection module only needs to increase the control node and modify the upper level. The test result shows that the new intelligent hematology analyzer based on the distributed architecture has good reliability and scalability, and can realize the rapid expansion of external modules.